What do you want from me?.. goes a song by Pink Floyd. I believe this is one question you have to answer all the time. A “normal” person would say this line to his parents, to his wife, to his girlfriend, his boss, and to anyone else “he” cares about. My understanding of this statement is that it is an exasperated retort when the expectations are not fulfilled. Does it mean that he has already given his best and it wasn’t good enough? Does he not know what is expected of him? Or in his defense, the other person is just hard to please. The other tricky part is that the answer to that question varies all the time. An answer which was “correct” on one occasion need not be the correct albeit to the same person in another point of time. The one who knows the answer, I think will be the enlightened one. I believe “doing the right thing” is the correct answer all the time. But who does (who wants to?) do the right thing all the time!
The Hitchhiker’s Guide to the Galaxy talks about the Ultimate Answer. This, I think would be in contention for the “Ultimate Question”.